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NCT04513639: Phase 2/3: The Relapse From MRD Negativity as Indication for Treatment (REMNANT) Study

Updated: May 25, 2022

NCT04513639: Phase 2/3: The Relapse From MRD Negativity as Indication for Treatment (REMNANT) Study


Dara-Kd

REMNANT Study Dara-Kd-MRD-Norway-Oslo

The Relapse From MRD Negativity as Indication for Treatment (REMNANT) Study


The REMNANT study will evaluate whether treating minimal residual disease (MRD) relapse after first line treatment prolongs progression free survival and overall survival for myeloma patients versus treating relapse after first line treatment at progressive disease. To establish a homogenous group of MRD negative patients after first line treatment including autologous stem cell transplantation, patients are enrolled at diagnosis and treated with Norwegian standard of care first line treatment. MRD negative patients will move on to the randomized part.


Sponsor:

Oslo University Hospital


Collaborators:

St. Olavs Hospital

Haukeland University Hospital

University Hospital of North Norway

University Hospital, Akershus

Helse Stavanger HF</