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NCT05461209: Phase 3: Talquetamab Vs Belantamab Mafodotin RRMM - (MonumenTAL-5)

(MonumenTAL-5)

NCT05461209: Phase 3: A Study of Comparing Talquetamab to Belantamab Mafodotin in Participants With Relapsed/Refractory Multiple Myeloma (MonumenTAL-5)

Talquetamab Vs Belantamab Mafodotin RRMM - (MonumenTAL-5)

NCT05461209: Phase 3: A Study of Comparing Talquetamab to Belantamab Mafodotin in Participants With Relapsed/Refractory Multiple Myeloma (MonumenTAL-5)


The purpose of this study is to compare the efficacy of talquetamab versus belantamab mafodotin in terms of overall response rate (ORR) or progression-free survival (PFS).


Sponsor

Janssen Research & Development, LLC

 

ClinicalTrials.gov Identifier: NCT05461209

Official Title: A Phase 3 Study Comparing Talquetamab to Belantamab Mafodotin in Participants With Relapsed/Refractory Multiple Myeloma Who Have Received at Least 4 Prior Therapies Including an Immunomodulatory Drug, a Proteasome Inhibitor, and an Anti-CD38 Antibody

First Posted : July 18, 2022

Click here to see details on ClinicalTrials.gov

 

Talquetamab

Talquetamab (Code C171840)

Anti-CD3/Anti-GPRC5D Bispecific Monoclonal Antibody JNJ-64407564

GPRC5D x CD3 Bispecific Antibody JNJ-64407564

GPRC5D x CD3 DuoBody Antibody JNJ-64407564

GPRC5D/CD3 DuoBody Antibody JNJ-64407564

Humanized GPRC5D x CD3 DuoBody Antibody JNJ-64407564

JNJ 64407564

JNJ-64407564

JNJ64407564

Talquetamab

TALQUETAMAB

 

Drug: Talquetamab

Drug: Belantamab Mafodotin

 

Locations

United States, Arkansas

United States, California

United States, District of Columbia

United States, Louisiana

United States, Maryland

United States, Massachusetts

United States, Michigan

United States, Minnesota

United States, Missouri

United States, New Jersey

United States, North Carolina

United States, Ohio

United States, Pennsylvania

United States, Texas

United States, Utah

United States, Wisconsin

Canada, Nova Scotia

Canada, Ontario

Canada, Quebec

Canada

Europe

Czechia

Germany

Israel

Italy

Poland

Portugal

Spain

United Kingdom

 

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