• Completed

NCT00511238: Phase 2 Study of Carfilzomib in Relapsed and Refractory Multiple Myeloma

Updated: Jun 13

RRMM

Relapsed and Refractory Multiple Myeloma

NCT00511238: Phase 2 Study of Carfilzomib in Relapsed and Refractory Multiple Myeloma

carfilzomib

NCT00511238: Phase 2 Study of Carfilzomib in Relapsed and Refractory Multiple Myeloma


To evaluate the overall response rate and safety and tolerability of carfilzomib in subjects with relapsed and refractory multiple myeloma. Patients must have received prior treatment with bortezomib and either thalidomide or lenalidomide and be refractory to their last treatment.


Sponsor

Amgen


Multiple Locations

International Study

 

ClinicalTrials.gov Identifier: NCT00511238


Official Title: An Open-label, Single-arm, Phase 2 Study of Carfilzomib in Patients With Relapsed and Refractory Multiple Myeloma

First Posted : August 3, 2007


Click here to see details on clinicaltrials.gov

 

Carfilzomib : National Cancer Institute

Carfilzomib : MedlinePlus Drug Information


Dexamethasone : National Cancer Institute

Dexamethasone : MedlinePlus Drug Information

 

A phase 2 study of single-agent carfilzomib (PX-171-003-A1) in patients with relapsed and refractory multiple myeloma

Blood; 2012 Oct

https://pubmed.ncbi.nlm.nih.gov/22833546/

 

Drug: carfilzomib

 

- Arizona: Mayo Clinic Arizona

- California: City of Hope Duarte

- California: University of California San Francisco

- Florida: Moffitt Cancer Center Tampa

- Georgia: Emory University Atlanta

- Illinois: Rush University Medical Center Chicago

- Minnesota: Mayo Clinic Rochester Minnesota

- Missouri: Washington University School of Medicine Saint Louis

- New Jersey: Hackensack University Medical Center

- New York: Roswell Park Cancer Institute Buffalo

- North Carolina: Wake Forest Baptist Health Winston-Salem

- Pennsylvania: University of Pennsylvania Philadelphia

- Tennessee: Sarah Cannon Research Institute Nashville

- Texas: The University of Texas MD Anderson Cancer Center Houston

 

Locations

United States, Alabama

United States, Arizona

United States, California

United States, Florida

United States, Georgia

United States, Illinois

United States, Kentucky

United States, Michigan

United States, Minnesota

United States, Missouri

United States, New Jersey

United States, New York

United States, North Carolina

United States, Ohio

United States, Pennsylvania

United States, Tennessee

United States, Texas

United States, Utah

Canada, Alberta

Canada, British Columbia

Canada, Ontario

Canada, Quebec

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