NCT01169337: Phase 3 -Lenalidomide or Observation in Asymptomatic High-Risk Smoldering Myeloma E3A06
- Active, not recruiting
- Dec 10, 2010
- 2 min read
Updated: May 23, 2022
ECOG E3A06
ECOG-ACRIN Cancer Research Group
ECOG E3A06
Lenalidomide or Observation in Treating Patients With Asymptomatic High-Risk Smoldering Multiple Myeloma
This randomized phase II/III trial studies how well lenalidomide works and compares it to observation in treating patients with asymptomatic high-risk asymptomatic (smoldering) multiple myeloma. Biological therapies such as lenalidomide, may stimulate the immune system in different ways and stop cancer cells from growing. Sometimes the cancer may not need treatment until it progresses. In this case, observation may be sufficient. It is not yet known whether lenalidomide is effective in treating patients with high-risk smoldering multiple myeloma than observation alone.
Sponsor
National Cancer Institute (NCI)
ClinicalTrials.gov Identifier: NCT01169337
Official Title: Randomized Phase III Trial of Lenalidomide Versus Observation Alone in Patients With Asymptomatic High-Risk Smoldering Multiple Myeloma
First Posted : July 26, 2010
Click here for details on ClinicalTrials.gov
J Clin Oncol; 2020 Apr
Conclusion: Early intervention with lenalidomide in smoldering multiple myeloma significantly delays progression to symptomatic multiple myeloma and the development of end-organ damage.
2019 ASCO Annual Meeting
Abstract 8001
* Lenalidomide (Revlimid)
Locations
United States, Alaska
United States, Arizona
United States, California
United States, Colorado
United States, Connecticut
United States, Delaware
United States, District of Columbia
United States, Florida
United States, Georgia
United States, Idaho
United States, Illinois
United States, Indiana
United States, Iowa
United States, Kansas
United States, Kentucky
United States, Louisiana
United States, Maine
United States, Maryland
United States, Massachusetts
United States, Michigan
United States, Minnesota
United States, Mississippi
United States, Missouri
United States, Montana
United States, Nebraska
United States, Nevada
United States, New Jersey
United States, New Mexico
United States, New York
United States, North Carolina
United States, North Dakota
United States, Ohio
United States, Oklahoma
United States, Oregon
United States, Pennsylvania
United States, South Carolina
United States, South Dakota
United States, Tennessee
United States, Texas
United States, Vermont
United States, Virginia
United States, Washington
United States, West Virginia
United States, Wisconsin
United States, Wyoming
Puerto Rico
Europe
Ireland
