NCT00574288: Phase 1/2: Daratumumab (HuMax®-CD38) Safety Study in Multiple Myeloma - GEN501 study

GEN501 study

Daratumumab (HuMax®-CD38) Safety Study in Multiple Myeloma

Establishment of safety profile of HuMax-CD38 when given as monotherapy in participants with multiple myeloma relapsed from or refractory to at least 2 different cytoreductive therapies and without further established treatment options.

Multiple Locations

International Study

ClinicalTrials.gov Identifier: NCT00574288

Official Title: Daratumumab (HuMax®-CD38) Safety Study in Multiple Myeloma - Open Label, Dose-escalation Followed by Open Label, Single-arm Study

---

Daratumumab : National Cancer Institute

Daratumumab : MedlinePlus Drug Information

---

Publications:

Daratumumab monotherapy in patients with heavily pretreated relapsed or refractory multiple myeloma: final results from the phase 2 GEN501 and SIRIUS trials.

Lancet Haematol. 2020 Jun;7

Targeting CD38 with Daratumumab Monotherapy in Multiple Myeloma.

N Engl J Med. 2015 Sep 24