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NCT04960579: Phase 1: P-BCMA-ALLO1 Allogeneic CAR-T Cells in the Treatment of Multiple Myeloma

NCT04960579: Phase 1: P-BCMA-ALLO1 Allogeneic CAR-T Cells in the Treatment of Subjects With Multiple Myeloma (MM)


P-BCMA-ALLO1


NCT04960579: Phase 1: P-BCMA-ALLO1 Allogeneic CAR-T Cells in the Treatment of Subjects With Multiple Myeloma (MM)


Phase 1 study comprised of open-label, dose escalation, multiple cohorts of P-BCMA-ALLO1 allogeneic T stem cell memory (Tscm) CAR-T cells in subjects with relapsed / refractory Multiple Myeloma (RRMM).


Sponsor

Poseida Therapeutics, Inc

 

ClinicalTrials.gov Identifier: NCT04960579

Official Title: Open-Label, Multicenter, Phase 1 Study to Assess the Safety of P-BCMA-ALLO1 in Subjects With Relapsed / Refractory Multiple Myeloma (MM)

First Posted : July 14, 2021


Click here for details on Clinicaltrials.gov

 

Drug: Rimiducid


Allogeneic Anti-BCMA CAR T Cells P-BCMA-ALLO1


Allogeneic Anti-BCMA CAR T Cells P-BCMA-ALLO1 (Code C181747)

Allogeneic Anti-BCMA CAR T Cells P-BCMA-ALLO1

Allogeneic Anti-BCMA-CAR-expressing Tscm P-BCMA-ALLO1

Allogeneic Tscm-rich Anti-BCMA CAR T Cells P-BCMA-ALLO1

P-BCMA-ALLO 1

P-BCMA-ALLO-1

P-BCMA-ALLO1

 

Biological: P-BCMA-ALLO1 CAR-T cells

Drug: Rimiducid

 

3858 Clinical Trials of BCMA-Targeted CAR-T Cells Utilizing a Novel Non-Viral Transposon System

Program: Oral and Poster Abstracts

Session: 704. Cellular Immunotherapies: Clinical: Poster III

Hematology Disease Topics & Pathways:

Biological therapies, Chimeric Antigen Receptor (CAR)-T Cell Therapies, Therapies

Monday, December 13, 2021, 6:00 PM-8:00 PM

Click here for details

 

Poseida Therapeutics Provides Update on BCMA-Targeted CAR-T Clinical Trials at the 2021 American Society of Hematology (ASH) Annual Meeting

SAN DIEGO, Dec. 13, 2021 /PRNewswire/ -- Poseida Therapeutics, Inc. (Nasdaq: PSTX), a clinical-stage biopharmaceutical company utilizing proprietary genetic engineering platform technologies to create cell and gene therapeutics with the capacity to cure, today reported interim results from its Phase 1/2 PRIME clinical trial of P-BCMA-101 for the treatment of relapsed/refractory multiple myeloma (R/R MM) at the 2021 American Society of Hematology (ASH) Annual Meeting.


Click here for details

 

Locations

United States, California

United States, Illinois

United States, Maryland

United States, Oklahoma

United States, Texas




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