- Recruiting
NCT02343042: Phase 1/2 - Selinexor and Backbone Treatments of Multiple Myeloma Patients (STOMP)
Updated: Oct 23, 2022
STOMP
Selinexor and Backbone Treatments of Multiple Myeloma Patients (STOMP)
This study will independently assess the efficacy and safety of 10 combination therapies in 11 arms, in dose-escalation/-evaluation and expansion phases, for the treatment of patients with relapsed/refractory multiple myeloma (RRMM) and newly diagnosed multiple myeloma (NDMM).
Selinexor and Backbone Treatments of Multiple Myeloma Patients (STOMP)
Sponsor
ClinicalTrials.gov Identifier: NCT02343042
Official Title: A Phase 1b/2 Study of Selinexor (KPT-330) in Combination With Backbone Treatments for Relapsed/Refractory Multiple Myeloma and Newly Diagnosed Multiple Myeloma
First Posted : January 21, 2015
Click here for details on ClinicalTrials.gov
Selinexor : National Cancer Institute
Selinexor : MedlinePlus Drug Information
Selinexor plus low-dose bortezomib and dexamethasone for patients with relapsed or refractory multiple myeloma.
Blood. 2018 Dec 13
1651 Efficacy and Safety of Selinexor-Containing Regimens in Patients with Multiple Myeloma Previously Treated with Anti-CD38 Monoclonal Antibodies (αCD38 mAb)
Program: Oral and Poster Abstracts
Session: 653. Myeloma and Plasma Cell Dyscrasias: Clinical-Prospective Therapeutic Trials: Poster I
Hematology Disease Topics & Pathways:
Clinical Trials, Acute Myeloid Malignancies, Adults, Clinical Research, Study Population
Saturday, December 11, 2021, 5:30 PM-7:30 PM
Once weekly selinexor, carfilzomib and dexamethasone in carfilzomib non-refractory multiple myeloma patients
Br J Cancer. 2022 Mar 23
Drug: Selinexor
Drug: Dexamethasone
Drug: Lenalidomide
Drug: Pomalidomide
Drug: Bortezomib
Drug: Daratumumab
Drug: Carfilzomib
Drug: Ixazomib
Drug: Elotuzumab
Drug: Clarithromycin
Drug: Belantamab Mafodotin
- Colorado: Sarah Cannon/Colorado Blood Cancer Institute Denver
- Massachusetts: Dana-Farber Cancer Institute/Harvard Cancer Center Boston
- Massachusetts: Massachusetts General Hospital Boston
- New Jersey: Hackensack University Medical Center
- New York: Columbia University Medical Center New York
- New York: New York Presbyterian / Weill Cornell Medical College New York
- New York: University of Rochester New York
- Nebraska: University of Nebraska Medical Center Omaha
- Tennessee: Sarah Cannon Research Institute Nashville
Locations
United States, Arizona
United States, California
United States, Colorado
United States, Massachusetts
United States, Nebraska
United States, New Jersey
United States, New York
United States, North Carolina
United States, Tennessee
United States, Washington
United States, Wisconsin
Canada, Alberta
Canada, British Columbia
Canada, Manitoba
Canada, Newfoundland and Labrador
Canada, Nova Scotia
Canada, Ontario
Canada, Quebec