NCT00048230: Phase 3 - PS-341 (VELCADE™) Versus High-Dose Dexamethasone in Patients With RRMM

Phase 3 - PS-341 (VELCADE™) Versus High-Dose Dexamethasone in Patients With Relapsed or Refractory Multiple Myeloma

NCT00048230

This study will compare the efficacy of PS-341 versus high dose dexamethasone.

Sponsor: Millennium Pharmaceuticals, Inc.

Multiple locations

International Study

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ClinicalTrials.gov Identifier: NCT00048230

Official Title: An International, Multi-Center, Randomized, Open-Label Study of PS-341 (VELCADE™) Versus High-Dose Dexamethasone in Patients With Relapsed or Refractory Multiple Myeloma

https://clinicaltrials.gov/ct2/show/NCT00048230

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Bortezomib : National Cancer Institute

Bortezomib : MedlinePlus Drug Information

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Drug: Bortezomib

Bortezomib

bortezomib

BORTEZOMIB

LDP 341

MLN341

PS-341

PS341

velcade

Velcade

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Retrospective matched-pairs analysis of bortezomib plus dexamethasone versus bortezomib monotherapy in relapsed multiple myeloma

Haematologica; 2015

https://pubmed.ncbi.nlm.nih.gov/25261096/

Sequence analysis of β-subunit genes of the 20S proteasome in patients with relapsed multiple myeloma treated with bortezomib or dexamethasone

Blood; 2012

https://pubmed.ncbi.nlm.nih.gov/23018640/

Impact of prior therapies on the relative efficacy of bortezomib compared with dexamethasone in patients with relapsed/refractory multiple myeloma

Br J Haematol; 2009

https://pubmed.ncbi.nlm.nih.gov/19725827/