• Completed

NCT02252263: Phase 1: Elotuzumab (BMS-901608) With Lirilumab (BMS-986015) or Urelumab (BMS-663513)

NCT02252263: Phase 1: A Phase I Open Label Study of the Safety and Tolerability of Elotuzumab (BMS-901608) Administered in Combination With Either Lirilumab (BMS-986015) or Urelumab (BMS-663513) in Subjects With Multiple Myeloma


Elotuzumab (BMS-901608) With Lirilumab (BMS-986015) or Urelumab (BMS-663513)

A Phase I Open Label Study of the Safety and Tolerability of Elotuzumab (BMS-901608) Administered in Combination With Either Lirilumab (BMS-986015) or Urelumab (BMS-663513) in Subjects With Multiple Myeloma


To assess the safety and tolerability, characterize the dose limiting toxicities (DLTs) and identify the maximally tolerated dose (MTD) of Elotuzumab administered in combination with either Lirilumab or Urelumab in subjects with multiple myeloma.



Sponsor

Bristol-Myers Squibb

 

ClinicalTrials.gov Identifier: NCT02252263

Official Title: A Phase I Open Label Dose Escalation and Randomized Cohort Expansion Study of the Safety and Tolerability of Elotuzumab (BMS-901608) Administered in Combination With Either Lirilumab (BMS-986015) or Urelumab (BMS-663513) in Subjects With Multiple Myeloma

First Posted : September 30, 2014

Click here for details on ClinicalTrials.gov

 

Elotuzumab

Elotuzumab (Code C66982)

BMS-901608

Elotuzumab

ELOTUZUMAB

Empliciti

HuLuc-63

HuLuc63

PDL-063

PDL063

anti-CS1 monoclonal antibody HuLuc63


Lirilumab

Lirilumab (Code C103820)

BMS-986015

IPH2102

Lirilumab

LIRILUMAB

anti-KIR monoclonal antibody IPH2102


Urelumab

Urelumab (Code C62449)

BMS-663513

Immunoglobulin G4, Anti-(Human Receptor 4-1BB) (Human Gamma-Chain), Disulfide with Human Kappa-Chain, Dimer

Urelumab

URELUMAB

anti-4-1BB monoclonal antibody

anti-CD137 monoclonal antibody

 

Drug: Elotuzumab

Drug: Lirilumab

Drug: Urelumab

 

Location

United States, Arkansas

United States, Maryland

United States, New York

United States, Ohio

United States, Oregon

United States, Pennsylvania

Europe

Spain





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