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NCT05231629: Phase 2: Sequential Therapy in Multiple Myeloma Guided by MRD Assessments (MASTER-2)

Updated: Feb 7

MASTER-2

NCT05231629: Phase 2: Sequential Therapy in Multiple Myeloma Guided by MRD Assessments (MASTER-2)


master 2 trial myeloma MRD Costa

NCT05231629: Phase 2: Sequential Therapy in Multiple Myeloma Guided by MRD Assessments (MASTER-2)


This research study will determine the proportion of patients with lowest minimal residual disease (MRD) response obtainable after receiving 6 cycles of study treatment. Minimal residual disease is multiple myeloma cells below the level of 1 cancer cell out of 100,000 in the bone marrow.


Sponsor


Collaborator

 

ClinicalTrials.gov Identifier: NCT05231629

Official Title: MRD-Guided Sequential Therapy For Deep Response in Newly Diagnosed Multiple Myeloma - MASTER-2 Trial

First Posted: February 9, 2022


Click here for details on ClinicalTrials.gov

 

Drug: Dara-VRd intensification, Dara-R maintenance

Drug: AHCT intensification, Dara-R maintenance

Drug: AHCT intensification, Tec-Dara consolidation, Tec-Dara maintenance

Drug: AHCT intensification, Dara-R consolidation, Dara-R maintenance

Drug: Dara-VRd induction

 

Locations

United States, Alabama

 

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