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NCT02786511: Longterm Follow-up of Subjects Treated With bb2121

Updated: Sep 27

NCT02786511: Longterm Follow-up of Subjects Treated With bb2121

bb2121

NCT02786511: Longterm Follow-up of Subjects Treated With bb2121


This is a multi-center, non-randomized, open label, longterm safety and efficacy follow-up study for subjects who have been treated with bb2121 in the Phase 1 clinical parent study, that evaluated the safety and efficacy of bb2121 in subjects with relapsed or refractory B cell maturation antigen (BCMA)-expressing multiple myeloma.bb2121 is defined as autologous T lymphocytes (T cells) transduced ex vivo with anti-BCMA02 CAR lentiviral vector encoding the chimeric antigen receptor (CAR) targeted to human BCMA suspended in cryopreservative solution.


bb2121 is administered in subjects 1 time (or retreated if retreatment criteria are met) in parent clinical study. No investigational treatment will be administered in this study. After completing the parent study, eligible subjects will be followed for up to 15 years after their last bb2121 infusion in the parent study.


Sponsor

Celgene

 

ClinicalTrials.gov Identifier: NCT02786511

Official Title: Longterm Follow-up of Subjects Treated With bb2121

First Posted: June 1, 2016

Click here for details on ClinicalTrials.gov

 

CART - BCMA : National Cancer Institute

Idecabtagene Vicleucel : National Cancer Institute

Idecabtagene Vicleucel : MedlinePlus Drug Information

 

* Idecabtagene Vicleucel

* bb2121

* Bluebird Bio

 

- National Cancer Institute (NCI)

- Massachusetts: Dana-Farber Cancer Institute/Harvard Cancer Center Boston

- Massachusetts: Massachusetts General Hospital Boston

- New Jersey: Hackensack University Medical Center

- Minnesota: Mayo Clinic Rochester Minnesota

- New York: Tisch Cancer Institute Mount Sinai Hospital New York

- Tennessee: Sarah Cannon Research Institute Nashville

 

Locations

United States, California

United States, Maryland

United States, Massachusetts

United States, Minnesota

United States, New Jersey

United States, New York

United States, Tennessee

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