• Active, not recruiting

NCT01592370: Phase 1/2: Safety and Effectiveness of Nivolumab and Daratumumab in Multiple Myeloma

NCT01592370: Phase 1/2: An Investigational Immuno-Therapy Study to Determine the Safety and Effectiveness of Nivolumab and Daratumumab in Patients With Multiple Myeloma


nivo-dara

The purpose of this study is to determine the side effects of treatment of the combination of nivolumab and daratumumab in participants with relapsed/refractory multiple myeloma.


Sponsor

Bristol-Myers Squibb


Collaborator

Janssen, LP

 

ClinicalTrials.gov Identifier: NCT01592370

Official Title: Multiple Phase 1/2 Cohorts of Nivolumab Monotherapy or Nivolumab Combination Regimens Across Relapsed/Refractory Hematologic Malignancies

First Posted : May 7, 2012

Click here for details on ClinicalTrials.gov

 

Nivolumab

Nivolumab (Code C68814)

BMS-936558

CMAB819

MDX-1106

NIVO

Nivolumab

NIVOLUMAB

Nivolumab Biosimilar CMAB819

ONO-4538

Opdivo


Ipilimumab

Ipilimumab (Code C2654)

Anti-Cytotoxic T-Lymphocyte-Associated Antigen-4 Monoclonal Antibody

BMS-734016

Ipilimumab

IPILIMUMAB

ipilimumab

Ipilimumab Biosimilar CS1002

MDX-010

MDX-CTLA4

Yervoy


Lirilumab

Lirilumab (Code C103820)

BMS-986015

IPH2102

Lirilumab

LIRILUMAB

anti-KIR monoclonal antibody IPH2102


Daratumumab

Daratumumab (Code C74007)

Anti-CD38 Monoclonal Antibody

Daratumumab

DARATUMUMAB

Darzalex

HuMax-CD38

JNJ-54767414

 

Biological: Nivolumab

Biological: Ipilimumab

Biological: Lirilumab

Biological: Daratumumab


Drug: Pomalidomide

Drug: Dexamethasone

 

J Clin Oncol; 2016

Nivolumab in Patients With Relapsed or Refractory Hematologic Malignancy: Preliminary Results of a Phase Ib Study

Click here for details

 

Location

United States, California

United States, Colorado

United States, Connecticut

United States, Florida

United States, Indiana

United States, Kansas

United States, Maryland

United States, Massachusetts

United States, Michigan

United States, Minnesota

United States, Nebraska

United States, New Jersey

United States, New York

United States, Ohio

United States, Oregon

United States, Pennsylvania

United States, Utah

Europe

Belgium

France

Greece

Italy

Poland




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