• Not yet recruiting

NCT05257083: Phase 3: EMN 28 - DVRd -> Cilta-Cel (CART) Vs DVRd -> Transplant ASCT- NDMM CARTITUDE-6

EMN 28

European Myeloma Network

EMN28/68284528MMY3005


NCT05257083: Phase 3 : A Study of Daratumumab, Bortezomib, Lenalidomide and Dexamethasone (DVRd) Followed by Ciltacabtagene Autoleucel Versus Daratumumab, Bortezomib, Lenalidomide and Dexamethasone (DVRd) Followed by Autologous Stem Cell Transplant (ASCT) in Participants With Newly Diagnosed Multiple Myeloma (CARTITUDE-6)

CARTITUDE6

A Study of Daratumumab, Bortezomib, Lenalidomide and Dexamethasone (DVRd) Followed by Ciltacabtagene Autoleucel Versus Daratumumab, Bortezomib, Lenalidomide and Dexamethasone (DVRd) Followed by Autologous Stem Cell Transplant (ASCT) in Participants With Newly Diagnosed Multiple Myeloma (CARTITUDE-6)


The purpose of this study is to compare the efficacy of Daratumumab, Bortezomib, Lenalidomide and Dexamethasone (DVRd) followed by Ciltacabtagene Autoleucel versus Daratumumab, Bortezomib, Lenalidomide and Dexamethasone (DVRd) followed by Autologous Stem Cell Transplant (ASCT) in newly diagnosed multiple myeloma patients.

EMN 28


Sponsor

European Myeloma Network

Collaborator

Janssen Research & Development, LLC


Legend Biotech

 

ClinicalTrials.gov Identifier: NCT05257083

Official Title: A Phase 3 Randomized Study Comparing Daratumumab, Bortezomib, Lenalidomide and Dexamethasone (DVRd) Followed by Ciltacabtagene Autoleucel Versus Daratumumab, Bortezomib, Lenalidomide and Dexamethasone (DVRd) Followed by Autologous Stem Cell Transplant (ASCT) in Participants With Newly Diagnosed Multiple Myeloma Who Are Transplant Eligible

First Posted: February 25, 2022

Click here for details on ClinicalTrials.gov


EMN28 - European Myeloma Network (myeloma-europe.org)

 

CART - BCMA : National Cancer Institute

JNJ-68284528 - ciltacabtagene autoleucel


CART

JNJ-68284528

Ciltacabtagene Autoleucel

 

Drug: Daratumumab

Drug: Bortezomib

Drug: Lenalidomide

Drug: Dexamethasone

Drug: Cilta-cel

Drug: Cyclophosphamide

Drug: Fludarabine

 

Locations

Australia

Europe

Germany

Spain

Netherlands

Belgium

Italy

Czechia

Switzerland

Greece

Asia

Israel

Korea, Republic of

 

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