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NCT04246047: Phase 3: Belantamab Mafodotin, Bortezomib and Dex RRMM Myeloma (DREAMM 7)

Updated: Sep 19, 2022

NCT04246047: Phase 3: Evaluation of Efficacy and Safety of Belantamab Mafodotin, Bortezomib and Dexamethasone Versus Daratumumab, Bortezomib and Dexamethasone in Participants With Relapsed/Refractory Multiple Myeloma (DREAMM 7)

Dreamm 7 belantamab

NCT04246047: Phase 3: Evaluation of Efficacy and Safety of Belantamab Mafodotin, Bortezomib and Dexamethasone Versus Daratumumab, Bortezomib and Dexamethasone in Participants With Relapsed/Refractory Multiple Myeloma (DREAMM 7)


This is a Phase 3, randomized, open-label study designed to evaluate safety and efficacy of belantamab mafodotin in combination with bortezomib/dexamethasone (Arm A) versus daratumumab in combination with bortezomib/dexamethasone (Arm B) in the participants with relapsed recurrent multiple myeloma.


Sponsor

GlaxoSmithKline

 

ClinicalTrials.gov Identifier: NCT04246047 Official Title: DREAMM 7: A Multicenter, Open-Label, Randomized Phase III Study to Evaluate the Efficacy and Safety of the Combination of Belantamab Mafodotin, Bortezomib, and Dexamethasone (B-Vd) Compared With the Combination of Daratumumab, Bortezomib and Dexamethasone (D-Vd) in Participants With Relapsed/Refractory Multiple Myeloma

First Posted : January 29, 2020

Click here for details on ClinicalTrials.gov


DREAMM Clinical Trial Program (dreammtrials.com)

 

Belantamab mafodotin : National Cancer Institute

Belantamab mafodotin : MedlinePlus Drug Information

GSK2857916

 

Drug: Belantamab mafodotin

Drug: Daratumumab

Drug: Bortezomib

Drug: Dexamethasone

 

3247 DREAMM-7: A Phase III Study of the Efficacy and Safety of Belantamab Mafodotin (Belamaf) with Bortezomib, and Dexamethasone (B-Vd) in Patients with Relapsed/Refractory Multiple Myeloma (RRMM)

Program: Oral and Poster Abstracts

Session: 653. Myeloma/Amyloidosis: Therapy, excluding Transplantation: Poster III

Hematology Disease Topics & Pathways:

Diseases, drug-drug interaction, Therapies, Combinations, Plasma Cell Disorders, Lymphoid Malignancies

Monday, December 7, 2020, 7:00 AM-3:30 PM


Learn more

 

Locations

United States, Arizona

United States, Colorado

United States, Kansas

United States, Ohio

United States, Texas

United States, Virginia

Canada, Alberta

Canada, Ontario

Canada, Quebec


Australia, New South Wales

Australia, Queensland

Australia, South Australia

Australia, Victoria

Australia, Western Australia

Europe

Asia

United Kingdom

Belgium

Brazil

Czechia

France

Germany

Greece

Israel

Italy

Japan

Korea, Republic of

Netherlands

New Zealand

Poland

Russian Federation

Spain

China, Guangdong

China, Jiangsu

China, Jilin

China, Shandong

China, Zhejiang

China

 

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