- Active, not recruiting
NCT01850524: Phase 3 - TOURMALINE-MM2 - Oral Ixazomib + Lenalidomide/Dex Vs Placebo + Len/Dex NDMM
Updated: Oct 4, 2022
TOURMALINE-MM2
IXAZOMIB Plus Lenalidomide and Dexamethasone Versus Placebo Plus Lenalidomide and Dexamethasone in Adult Patients With Newly Diagnosed Multiple Myeloma
The purpose of this study is to provide continued access to ixazomib and/or lenalidomide to participants who are continuing to have clinical benefit and to continue collecting relevant safety data to monitor safety in participants with Newly Diagnosed Multiple Myeloma (NDMM) who are not eligible for stem cell transplant.
Sponsor
Millennium Pharmaceuticals, Inc.
ClinicalTrials.gov Identifier: NCT01850524
Official Title: A Phase 3, Randomized, Double-Blind, Multicenter Study Comparing Oral MLN9708 Plus Lenalidomide and Dexamethasone Versus Placebo Plus Lenalidomide and Dexamethasone in Adult Patients With Newly Diagnosed Multiple Myeloma
First Posted : May 9, 2013
Click here for details on clinicalTrials.gov
Dexamethasone : National Cancer Institute
Dexamethasone : MedlinePlus Drug Information
Ixazomib: National Cancer Institute
Ixazomib: MedlinePlus Drug Information
Lenalidomide: National Cancer Institute
Lenalidomide: MedlinePlus Drug Information
Drug: Ixazomib
Drug: Placebo
Drug: Dexamethasone
Drug: Lenalidomide
Oral ixazomib, lenalidomide, and dexamethasone for transplant-ineligible patients with newly diagnosed multiple myeloma
Blood; 2021
https://pubmed.ncbi.nlm.nih.gov/33763699/
- Multiple locations
- International study
- Alabama: University of Alabama at Birmingham
- Arkansas: University of Arkansas Little Rock
- Massachusetts: Dana-Farber Cancer Institute/Harvard Cancer Center Boston
- Minnesota: Mayo Clinic Rochester Minnesota
- Georgia: Emory University Atlanta
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