- Active, not recruiting
NCT01564537: Phase 3 - TOURMALINE-MM1 - Oral Ixazomib + Len/Dex Vs Placebo + Len/Dex RRMM
Updated: Oct 4, 2022
TOURMALINE-MM1
A Phase 3 Study Comparing Oral Ixazomib Plus Lenalidomide and Dexamethasone Versus Placebo Plus Lenalidomide and Dexamethasone in Adult Patients With Relapsed and/or Refractory Multiple Myeloma
A Phase 3 Study Comparing Oral Ixazomib Plus Lenalidomide and Dexamethasone Versus Placebo Plus Lenalidomide and Dexamethasone in Adult Patients With Relapsed and/or Refractory Multiple Myeloma
The purpose of this study is to determine whether the addition of oral ixazomib to the background therapy of lenalidomide and dexamethasone improves progression free survival (PFS) in participants with relapsed and/or refractory multiple myeloma (RRMM).
Sponsor
Millennium Pharmaceuticals, Inc.
Information provided by (Responsible Party)
Takeda ( Millennium Pharmaceuticals, Inc. )
ClinicalTrials.gov Identifier: NCT01564537
Official Title: A Phase 3, Randomized, Double-Blind, Multicenter Study Comparing Oral Ixazomib (MLN9708) Plus Lenalidomide and Dexamethasone Versus Placebo Plus Lenalidomide and Dexamethasone in Adult Patients With Relapsed and/or Refractory Multiple Myeloma
First Posted : March 28, 2012
Click here for details on ClinicalTrials.gov
Dexamethasone : National Cancer Institute
Dexamethasone : MedlinePlus Drug Information
Ixazomib: National Cancer Institute
Ixazomib: MedlinePlus Drug Information
Lenalidomide: National Cancer Institute
Lenalidomide: MedlinePlus Drug Information
Oral Ixazomib, Lenalidomide, and Dexamethasone for Multiple Myeloma.
N Engl J Med. 2016
Blood. 2017 Dec
Haematologica. 2017 Oct
J Hematol Oncol. 2017
Drug: Ixazomib
Drug: Lenalidomide
Drug: Dexamethasone
Drug: Placebo
- Arkansas: University of Arkansas Little Rock
- Massachusetts: Dana-Farber Cancer Institute/Harvard Cancer Center Boston
- Minnesota: Mayo Clinic Rochester Minnesota
- New Jersey: Hackensack University Medical Center
- New York: Columbia University Medical Center New York
- New York: Roswell Park Cancer Institute Buffalo
- Wisconsin: Medical College Of Wisconsin Milwaukee
- Washington: Fred Hutchinson Cancer Center Seattle
Locations
United States, Arkansas
United States, California
United States, Florida
United States, Georgia
United States, Illinois
United States, Massachusetts
United States, Minnesota
United States, New Jersey
United States, New York
United States, North Carolina
United States, Pennsylvania
United States, South Carolina
United States, Washington
United States, West Virginia
United States, Wisconsin
Canada, Alberta
Canada, British Columbia
Canada, New Brunswick
Canada, Quebec
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