• Active, not recruiting

NCT03652064 : Phase 3 - Bortezomib, Lenalidomide, Dex and +/- Daratumumab - NDMM - MMY3019 CEPHEUS

Updated: Sep 25

CEPHEUS Study

MMY3019

A Study Comparing Daratumumab, VELCADE (Bortezomib), Lenalidomide, and Dexamethasone (D-VRd) With VELCADE, Lenalidomide, and Dexamethasone (VRd) in Participants With Untreated Multiple Myeloma and for Whom Hematopoietic Stem Cell Transplant is Not Planned as Initial Therapy

CEPHEUS Study Dara rvd myeloma trial

The purpose of this study to determine if the addition of daratumumab to bortezomib + lenalidomide + dexamethasone (VRd) will improve overall minimal residual disease (MRD) negativity rate compared with VRd alone.


Sponsor

Janssen Research & Development, LLC


International Study

Multiple Locations

 

ClinicalTrials.gov Identifier: NCT03652064

Official Title: A Phase 3 Study Comparing Daratumumab, VELCADE (Bortezomib), Lenalidomide, and Dexamethasone (D-VRd) With VELCADE, Lenalidomide, and Dexamethasone (VRd) in Subjects With Untreated Multiple Myeloma and for Whom Hematopoietic Stem Cell Transplant is Not Planned as Initial Therapy

First Posted : August 29, 2018

Click here for details on ClinicalTrials.gov

 

Daratumumab : National Cancer Institute

Daratumumab : MedlinePlus Drug Information


Lenalidomide: National Cancer Institute

Lenalidomide: MedlinePlus Drug Information


Bortezomib: National Cancer Institute

Bortezomib: MedlinePlus Drug Information


Dexamethasone : National Cancer Institute

Dexamethasone : MedlinePlus Drug Information

 

Drug: Daratumumab

Drug: Bortezomib

Drug: Lenalidomide

Drug: Dexamethasone

 

- Massachusetts: Massachusetts General Hospital Boston

- New Jersey: Rutgers Cancer Institute of New Jersey New Brunswick

- New York: Roswell Park Cancer Institute Buffalo

- Ohio: Cleveland Clinic Ohio

- Pennsylvania: University of Pittsburgh Medical Center

- Texas: The University of Texas MD Anderson Cancer Center Houston

 

Locations

United States, California

United States, Florida

United States, Indiana

United States, Kentucky

United States, Massachusetts

United States, Michigan

United States, Missouri

United States, New Jersey

United States, New Mexico

United States, New York

United States, North Carolina

United States, Ohio

United States, Oregon

United States, Pennsylvania

United States, South Carolina

United States, Texas

United States, Virginia

Brazil

Canada

Canada, Alberta

Canada, British Columbia

Canada, Nova Scotia

Canada, Ontario

Canada, Quebec

Europe

United Kingdom

France

Germany

Netherlands

Spain

Czechia

Poland

Turkey

Asia

Israel

Japan

 

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