• Recruiting

NCT04483739: Phase 3: EMN 24 - Isa-KRd vs KRd New Multiple Myeloma Eligible for ASCT - IsKia TRIAL

Updated: Sep 25

(IsKia TRIAL) (IsKia) - (EMN24/HOVON503)

NCT04483739: Phase 3: Isa-KRd vs KRd in Newly Diagnosed Multiple Myeloma Patients Eligible for Autologous Stem Cell Transplantation (IsKia TRIAL) (IsKia)


IsKia trial (EMN24/HOVON503)

iskia - emn24

Isa-KRd vs KRd in Newly Diagnosed Multiple Myeloma Patients Eligible for Autologous Stem Cell Transplantation (IsKia TRIAL) (IsKia)


This protocol is a phase III study designed to compare the efficacy and the safety of Isa-KRd induction, transplant, Isa-KRd post ASCT consolidation and Isa-KRd light consolidation vs KRd induction, transplant, KRd post ASCT consolidation and KRd light consolidation After confirmation of eligibility criteria patients will be randomized to one of the 2 treatment groups in a 1:1 randomization ratio.


Sponsor

European Myeloma Network


Collaborators

EMN Research Italy

Sanofi

Amgen

 

ClinicalTrials.gov Identifier: NCT04483739

Official Title: Phase III Study of Isatuximab-Carfilzomib-Lenalidomide-Dexamethasone (Isa-KRd) Versus Carfilzomib-Lenalidomide-Dexamethasone (KRd) in Newly Diagnosed Multiple Myeloma Patients Eligible for Autologous Stem Cell Transplantation (IsKia TRIAL

First Posted: July 23, 2020

Click here for details on ClinicalTrials.gov


EMN24 - European Myeloma Network (myeloma-europe.org)


Click here for details on HOVON Website

 

Drug: Carfilzomib Lenalidomide Dexamethasone

Drug: Isatuximab Carfilzomib Lenalidomide Dexamethasone

 

Locations:

Europe

Czechia

Germany

Greece

Italy

Netherlands

Norway

Spain

 

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